Malegra 100 mg works by supporting the natural erectile response. During physical stimulation, nitric oxide is released in the penile tissues, which increases cyclic guanosine monophosphate (cGMP). This chemical relaxes smooth muscles and widens blood vessels, allowing more blood to flow into the pill. PDE5 normally breaks down cGMP, but Sildenafil inhibits this enzyme, maintaining higher levels of cGMP and helping sustain an erection. Importantly, physical arousal is still required; the medication does not cause automatic erections.
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