Zenegra 50 mg is a prescription medicine used to treat erectile dysfunction (ED) in men. It contains sildenafil citrate, a phosphodiesterase type 5 (PDE5) inhibitor that helps improve blood flow to the pill during physical stimulation, making it easier to achieve and maintain an erection. Sildenafil works by blocking the PDE5 enzyme, which normally breaks down cyclic guanosine monophosphate (cGMP). When PDE5 is inhibited, cGMP levels increase, leading to relaxation of smooth muscles and widening of blood vessels in the penile region. This improved blood flow supports a stronger erectile response, but the medicine only works when physical arousal is present—it does not cause spontaneous erections.
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